Kush Yadav, Ph.D candidate, and Dr. Scott Kenney recently published a paper in MDPI titled: Animal Models for Studying Congenital Transmission of Hepatitis E Virus. The review describes many of the current HEV animal model systems and the strengths and weaknesses of each as they apply to HEV pregnancy-associated mortality. Kush and Dr. Kenney consider factors that are critical to analyzing HEV infection within the host and how, despite no perfect animal model for human pregnancy mortality existing, recent developments in HEV models, both in vitro and in vivo, are advancing the overall understanding of HEV in the pregnant host.